Programmable RNA And Expression Control
Guided effectors that act on transcripts and protein output allow reversible tuning of gene expression without permanently altering genomic DNA.
Developed mainly in: Australia and United StatesImpacting: North America, Europe, China and Australia
Researchers led by Mohamed Fareh and colleagues at Peter MacCallum Cancer Centre report in Science Advances that PspCas13b guide RNAs designed to span fusion breakpoints degrade oncogenic fusion transcripts such as BCR-ABL while sparing the normal parent genes, killing fusion-positive cancer cells in preclinical models.
This is one of 24 signals scored in our latest scan.
Track Them Free For 14 Days →Since we flagged this
First flagged
21 May 2026 · score 8.0/10
Corroborating sources since flagging
25
Latest signals
Tracked from 3 signals, each traced to its source.
- Cas13b enzyme engineered to cut cancer fusion transcripts at breakpoint junctions
Science · 17 Oct 2026
- New CRISPR method makes it possible to control protein production in cells
Phys · 9 Jul 2026
- UF breakthrough could reshape RNA editing with world's first DNA-guided CRISPR News | University of Florida
News · 21 May 2026
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